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Dangerous Drugs?


 

"U.S. Says Doctors Overcharge Patients for Anti-Cancer Drugs"

From the New York Times on August 6, 2000 comes an article reporting on the view of the Medicare program that docs who administer chemo-therapy in their offices are taking a healthy (pun intended) mark-up on the treatment.

The bottomline in the deal is that now that the federal gubment better understands the mark-up docs are taking on the drugs they plan as early as October 1 to reduce the payment made to oncologist for office administered chemotherapy.

The docs say they are using the mark-up to cover overhead, the feds say they are gouging. The docs plan to just send the patient to a hospital someplace if they can't get the margins they are looking for... Marcus Welby where are you?

"High Tech Cures for Medical Errors"

The above is the title of an opinion piece appearing in the Washington Post written by the former speaker of the house the Honorable Newt Gingrich of Georgia.

On August 6, 2000, Newt waded in on the subject of medical error recounting the numbers from Lucian Leape regarding loaded planes crashing "Imagine that we had an airline crash every day, taking the lives of more than 250 Americans. The country would be outraged, the president would be demanding action and Congress would be passing emergency legislation. And yet a tragedy of similar proportions is occurring right now in American hospitals."

Newt goes on to call on Congress and the president to drag health care, kicking and screaming or going quietly, into the new millennium with "modern management information systems."

The solutions according to the former Speaker include the conversion of the prescription process to an electronic environment and the development of personal medical information systems. He cites a group in Las Vegas that has filled 50 million prescriptions without a single error and the newly designed patient information system at the Veteran's Administration Center in Palo Alto, California as examples of best practices.

His bottomline: Within three years every prescription written in the United States should be generated electronically and cross referenced for appropriateness etc with every patient file which has also been converted to an electronic form.

*** Hospital Cutbacks In Nursing Staff Deadly To Patients

A study done by The Chicago Tribune reports that hospitals across the country have quietly been eliminating their highest paid, best trained and most experienced nurses. This has led to numerous patient deaths directly due to overworked and under trained nursing staffs.

The author says that since 1995 at least 1720 hospital patients have been accidentally killed and 9584 others injured by nurses who are committing errors due to staff reductions and poor training. Because the process of reporting medical errors is so inadequate, the above figures likely only represent the tip of the iceberg.

In what is becoming a national trend among hospitals, even those that are doing well financially, the more educated, better trained registered nurses are being replaced with lesser trained, lower salaried practical nurses and aides. The reason? To increase or maintain profitability, even at the sacrifice of patient safety.

According to the study, the American Hospital Association (AHA) was warned by their president Dick Davidson in 1996 that the public was beginning to notice the "thinness" of nurse staffing.

Davidson said at the time that "Patients suffered, literally, because medications and vital, comforting services were delayed, confused or forgotten."

In commentary, we find it appalling that hospitals are cutting nursing staff as a way to increase profits. When patient safety becomes secondary to the bottom line, serious doubts arise about the intelligence and integrity of the people making those decisions. There is no greater responsibility in any health care system than the safety of the patient.

Drug Errors In Children Draw Alarm

Medscape reported on July 2, 2000 that errors in medication for children are creating a growing problem. The article states that the problem is due to the lack of information on the effects of many drugs on children. Most research is done with drugs on adults, little information is then known on the effects on children. The article states that improper dosage is the most common error that causes problems. They note that infants and children are not "little adults" and should not be treated as such. The article lists several facts demonstrating the "Big Problems". They are:

  • medication errors, excluding adverse reactions, are responsible for 14% of drug-related deaths
  • 5% of US hospital drug orders contain errors
  • 4 to 10% of US pharmacy-dispensed drugs involve some form of error; 0.6 to 1.5% of these are considered serious.
  • in France, 30% of pediatric calls to poison centers involve infants; the most common concern is an error of dose. Hospitalization is necessary in about 15% of cases.

Highlighting this problem is an article from Reuters News dated May 15, 2000 which headlines the fact that more children are being placed on a combination of medications such as Ritalin and Prozac. In this article Dr. Jerry Rushton of the University of Michigan in Ann Arbor, states, "I think the safety of these medications--in the young child especially--is not known, and when you take them in combination it is a whole new level of safety concern." The alarming numbers in this article show that by 1998, 10% of children aged 6 to 14 years were on Ritalin or stimulants, as were 1% of preschoolers aged 1 to 5 years.

Chiropractic care has long suggested that a proper functioning nervous system, free from interference creates a healthier functioning child. Studies done such as the one at Mississippi State University, published in the October 12, 1989 issue of the Journal of Manipulative and Physiological Therapeutics, showed that a non-drug approach can help children with hyperactivity. The researchers remarked, "the majority of the children in this study did, in fact, improve under specific chiropractic care."


Tuesday, June 27, 2000

Raising Kids To Be Drug Addicts? - From EagleForum.org comes an article titled, "Is Ritalin Raising Kids To Be Drug Addicts?"

The article states that "three to four million U.S. schoolchildren are using the controversial stimulant Ritalin" and that "its illicit use is providing a powerful kick to college students, too."

According to the article, it was found that "one in five college students on Ritalin are upping their doses or otherwise misusing their prescriptions" with some sharing their pills with friends.

The article states that some students "crush and snort Ritalin as a substitute for cocaine" and points out that, "methylphenidate [the key ingredient in Ritalin] is a central nervous system stimulant and shares many of the pharmacological effects of amphetamine, methamphetamine, and cocaine" according to a 1995 Drug Enforcement Administration report. According to the article, pediatric guidelines for diagnosing ADHD are "non - scientific" and "subjective." The article mentions that, "many high school shootings have been linked to prescribed mind-altering drugs." According to the article, "Oregon high school killer Kip Kinkel had been given Ritalin and Prozac, Columbine killer Eric Harris had taken another psychotropic drug, Georgia high school student T.J. Solomon had been on Ritalin prior to his alleged shooting spree, and Oklahoma middle school student Seth Trickey was on two drugs described to have psychotic effects when he allegedly shot at four students."

Although Ritalin has not been approved by the FDA for use by children under age six, the article states that "about one percent of children aged 2 to 4 are using Ritalin or Ritalin-like drugs, and that percentage is increasing rapidly."

What effect are these drugs having on children's nervous systems? Are they getting healthier by taking all these drugs?

EagleForum.org:


Friday February 9 1:21 PM ET

MMR Vaccine Does Not Cause Autism, Study Finds

By Suzanne Rostler
NEW YORK (Reuters Health) - A vaccine that is routinely given to millions of children each year does not cause autism, researchers report.

Their study adds to a growing body of evidence demonstrating that the measles/mumps/rubella (MMR) vaccine does not underlie a surge in the number of children who have been diagnosed with the disorder over the past 30 years.

According to the report in the February 17th issue of the British Medical Journal, the rate of autism rose sevenfold to 2.1 cases per 10,000 people per year in 1999, from 0.3 cases per 10,000 people per year in 1988 among children age 12 and younger in the UK. The rate of autism nearly quadrupled among boys aged 2 to 5 years to 29 cases per 10,000 people per year in 1998, from 8 cases per 10,000 people per year in 1993, results show.

But the rate of autism would not have continued to rise if MMR vaccine was a major cause, since the proportion of infants who received the vaccine remained stable at around 97% of infant ``Our finding an increasing risk of autism...while the MMR coverage was constant and nearly complete is evidence against a causal link between the MMR vaccine and the risk of autism,'' Dr. James A. Kaye of the Boston University School of Medicine in Lexington, Massachusetts, and the study's lead author, told Reuters Health.

He said an increased awareness, a broader definition of the disease and environmental factors that have not been identified may be to blame for the increasing rate of autism, a disorder that impairs language and normal social development. While the study could reassure parents about the safety of a vaccine that protects children against three potentially fatal illnesses, the researchers stress that the findings are not intended to provide recommendations.

``We hope that our...work will add important information to the ongoing discussions about the safety of the MMR vaccin (but we don't want to) make any specific recommendations about its use, which we believe is better left to individual doctors, , the UK Medicines Control Agency, and other professional medical groups,'' Kaye said in the interview. The study included 305 children age 12 and younger, who had been diagnosed with autism between 1988 and 1999. A subgroup of boys, who have a much higher rate of autism than girls, was also analyzed.

The investigators also found that about 83% of autism cases were boys and the peak age at which children were diagnosed with autism was 3 to 4 years.

SOURCE: British Medical Journal 2001;322:0-2.


Monday, March 12, 2001, 12:00 a.m. Pacific

Doctor bill for nation is soaring

by Anjetta McQueen
The Associated Press

WASHINGTON - The nation's annual bill for health care has risen to a record $1.2 trillion, with prescription drugs accounting for nearly 10 percent of the costs and expected to grab an even larger share of what Americans pay to get or stay healthy,government estimates show.

Overall health-care spending will more than double to $2.6 trillion by 2010, in part because drug costs are projected to rise on average 12.6 percent every year, federal health economists said in an annual report being published today.

Overall health-care spending includes such things as hospital-construction costs, but close to 90 percent is personal health-care spending: doctors' visits, hospitals stays, medicines and other medical services. The drug-spending boom - $99.6 billion in 1999, the latest year for which figures were available - comes not only with an aging population, but as more patients ask for newer, high-priced drugs marketed to them on television and take drug treatments at home for conditions that once landed them in hospitals, the report said.

Those trends could slow with an economic slowdown, when some employers and insurers could pass the growing costs onto consumers accustomed to low co-payments and other fees, said economists at the Health Care Financing Administration, which runs Medicare.

"There are going to be trade-offs," said Katharine Levit, economist on the spending report. "It puts increased pressure on all of us - the government, employers, providers - to somehow make choices in terms of how we spend our money." Consumer advocates say that patients who need prescription drugs will suffer in other ways if they do not get increased access to lower-cost generic drugs, expansive drug-coverage policies and lower premiums. "The personal cost is very real and very dramatic," said Gail Shearer, who handles health-cost issues for the Consumers Union, publisher of Consumer Reports magazine. "Children won't be getting the medicines they need to make them better. People of every age group will be suffering or they will have to neglect other basic needs." The government publishes the health-care-spending forecasts in the journal Health Affairs, projecting expenditures on health care by patients, their insurance plans and government programs.

In 1999, prescription drugs accounted for 9.4 percent of personal-health spending; by 2010, prescription drugs' share will be 16 percent, outpacing other services such as nursing homes and home-based health care, the report said. Prescription drugs also cut into Americans' out-of-pocket costs, expenses not offset by a private or government insurer. People spent $34.9 billion on drugs, compared with $12.6 billion for hospital care and $30.7 billion for doctor or clinic visits, the report said. The estimates have implications for the government as well.

The projected drug cost total for 2010 - $366 billion - does not take into account what could be spent on medicines if they were fully covered under the Medicare program.

Adding prescription-drug benefits to Medicare is a leading issue in Congress this year. President Bush and Senate lawmakers have competing plans on the table.

Observers say the forecasts only prove that Congress cannot leave Medicare participants - 39 million elderly and disabled Americans - unable to pay for valuable medicines.


Discredited diabetes drug got help from government

by David Willman
Los Angeles Times
CHUCK KENNEDY / KNIGHT RIDDER

Dr. John Gueriguian was pulled off the Rezulin assignment after he questioned the drug's safety.

WASHINGTON - Executives of the Warner-Lambert Co. brimmed with confidence as they marched the now-discredited diabetes pill Rezulin toward government approval in the mid-1990s. And with good reason, according to newly obtained company and government documents. As portrayed in the records, officials of the Food and Drug Administration (FDA) provided Warner-Lambert with inside information and favors at critical moments throughout the development and marketing of Rezulin. At least one Warner-Lambert senior manager believed that if an FDA medical officer who had questioned the drug's safety and effectiveness didn't please the company, he would be "out." Soon enough, he was, prompting another executive to report internally that a "hurdle" had been cleared for Rezulin. The records also shed new light on the state of knowledge within Warner-Lambert of Rezulin's potential danger: Executives knew that patients who took the drug in clinical studies had suffered life-threatening liver damage - yet the company assured an FDA panel that the risk was trivial.

The company's assurances helped win swift approval for Rezulin four years ago from the FDA. The drug was withdrawn in March of last year after being cited as the suspect in 391 deaths, including 63 that involved liver failure.

In the interim, Rezulin generated sales of $2.1 billion.

Internal memos and e-mails

The new documents, which have been kept from public view by court orders or by the FDA, were obtained by the Los Angeles Times. The internal memos and e-mails provide an intimate view of how a company seeking a blockbuster drug collaborated closely with the public-health agency responsible for ensuring that medicines are proved safe and effective. However, at the same time the FDA was being urged by Congress and the White House to function less as an adversary and more as a partner of the $100-billion-a-year pharmaceutical industry. This transformation of the FDA came after the agency's streamlined approvals of experimental AIDS drugs. Pharmaceutical companies pushed for similarly rapid consideration of new drugs for a wide range of disorders, regardless of whether the products offered life-saving benefits. And in Rezulin, the FDA was dealing with a drug that had not been proved to save lives or to reduce the serious complications of adult-onset diabetes.

'Comparable to placebo'

It was against this backdrop that Warner-Lambert's vice president for diabetes research, Dr. Randall Whitcomb, told an FDA advisory committee on Dec. 11, 1996, that occurrences of liver injury among Rezulin patients were "comparable to placebo" in the clinical studies. In fact, the incidence among patients who took the drug was more than three times greater than for those given placebo pills. Among those patients who took Rezulin, 2.2 percent experienced liver injury, compared to 0.6 percent for those who took the placebo. In a recent sworn deposition for lawsuits brought by plaintiffs from Texas, Missouri and West Virginia, Whitcomb defended his earlier characterizations.

" `Comparable' is, is, you know, is an interesting word," Whitcomb testified. "Is 2.2 percent different than 0.6 percent? ... I think you could look at 2.2 and 0.6 and say that those are similar numbers, you know, when you look at this now. I mean, `similar' is a, is a very broad term. ... I don't think that these numbers are, are all that different."

But documents reveal that concern about liver toxicity within Warner-Lambert was such that the company prepared a label for the drug in 1996 recommending that patients "should be monitored at 3 months then every 6 months." The company abandoned the recommendation for liver monitoring before seeking the FDA advisory committee's endorsement in December 1996. Such a condition would have drastically reduced Rezulin's sales potential, according to doctors who point out that at least nine less-risky diabetes drugs were available. Warner-Lambert did not publicly recommend liver monitoring for Rezulin patients until late October 1997 - and then only after the first reported liver-failure deaths among those who were prescribed the drug.

Whitcomb, 46, who was Warner-Lambert's chief medical proponent of Rezulin from 1993-2000, is now a part-time consultant to Pfizer, the parent company. Whitcomb did not return a phone call placed to his home.

No monitoring 'necessary'

In recent sworn testimony, Whitcomb said he and others at the company "did not believe monitoring was necessary at the time the product was launched."

However, at least 12 Rezulin patients in the studies were found to have potentially life-threatening liver toxicity, the records show, dating as early as 1993. All of the patients had markers of liver toxicity 10 to 30 times greater than the "upper limit of normal." Records show that before the drug was approved on Jan. 29, 1997, at least four Rezulin patients in clinical studies were known by the company or its consultants to have suffered jaundice, a complication that carries a 10 percent fatality rate. No instances of jaundice or other markers of life-threatening liver toxicity occurred among the placebo patients. On June 29, 1995, Whitcomb informed company-paid physicians testing Rezulin in the United States that a patient in Japan was hospitalized with jaundice after taking the drug for three months. "The Japanese investigator believed this hepatic dysfunction is probably related to (Rezulin)," Whitcomb wrote. But he concluded that in Warner-Lambert's opinion, "causality is indeterminable." In December 1996, Whitcomb assured the FDA's Endocrine and Metabolic Drugs Advisory Committee that Warner-Lambert had gathered results from clinical studies worldwide, yet he cited only one case of jaundice occurring among Rezulin patients.

"We also have all of the safety data from 629 patients from Europe," Whitcomb said. "And we have another 1,000 patients from Japan. ... We have all of the safety data available from that." It was not until March 26, 1998 - nearly six months after the first liver-failure deaths - that Whitcomb publicly acknowledged the severe liver-toxicity cases observed in clinical studies. Whitcomb did so not in a mass-mailed letter to physicians, but rather in a seven-paragraph letter published by the New England Journal of Medicine.

Two months later, a consultant hired by Warner-Lambert to prepare an inventory of liver injury among patients who were prescribed Rezulin complained that the company had understated the number of deaths. The inventory was to be submitted to the FDA by Warner-Lambert's Parke-Davis drug unit.

'Something is truly amiss'

"We have serious concerns about the case files generated for us by Parke-Davis," consultant Linda Miwa of the Degge Group Ltd., of Arlington, Va., wrote on May 5, 1998, to a Warner-Lambert vice president. " ... For example, the table of events lists five deaths. By our assessment, there are 14 liver deaths alone. We feel something is truly amiss here."

The documents show that more mistrust followed the liver failure and death, on May 17, 1998, of an East St. Louis, Ill., high-school teacher who had taken Rezulin in a diabetes-prevention study sponsored by Warner-Lambert and the National Institutes of Health. While the death prompted NIH officials to banish Rezulin from the ongoing study, an FDA medical officer, Dr. Robert Misbin, told a colleague in a July 22, 1998 e-mail: "Parke Davis is clearly unwilling to inform physicians about the grossly elevated liver enzymes which occured (sic) during the clinical trials. This is not surprizing (sic) because they did not inform the Advisory Committee either." Misbin had asked the company to acknowledge the cases in a "Dear Dr." letter to physicians nationwide.

A consultant to Warner-Lambert who helped conduct two of its studies alleged one year ago in a letter to Sen. Edward M. Kennedy, D-Mass., that the company "deliberately omitted reports of liver toxicity and misrepresented serious adverse events experienced by patients in their clinical studies." One of the cases involved a patient who was hospitalized with jaundice. The company denied the accusations, made by Dr. Janet McGill, a St. Louis endocrinologist.

FDA worked with company

Documents reveal that throughout Rezulin's rise and fall, senior FDA officials quietly collaborated with Warner-Lambert. Those who provided behind-the-scenes help to the company included Dr. Murray "Mac" Lumpkin, who now is among those being considered for appointment as FDA commissioner, and the chairman of the FDA advisory committee, Dr. Henry Bone III of Detroit.

One of the company's earliest concerns was the role of Dr. John Gueriguian, the FDA medical officer assigned in the early 1990s to examine Rezulin and its chemical class of drugs. Gueriguian, the newly obtained records show, voiced concern to Warner-Lambert as early as January 1994 about Rezulin's "potential toxicities."

The next year, Gueriguian challenged whether Warner-Lambert's proposed design for studying Rezulin in a forthcoming clinical trial would provide a legitimate evaluation of the drug's usefulness. On Aug. 7, 1995, the day before FDA officials were to meet internally to resolve the matter, Gueriguian's boss, Dr. G. Alexander Fleming, phoned a senior manager at Warner-Lambert, Mary E. Taylor. According to Taylor's memorandum, "Dr. Fleming asked me to call Dr. Gueriguian. ... He also offered that if our discussion did not go well, he would ease Dr. Gueriguian out." Taylor distributed this memo to six company executives.

One of those executives had written in a company e-mail on June 22, 1994, that he and Fleming had just discussed the company's "interactions" with Gueriguian. According to the e-mail, Fleming "implied that, while Dr. Gueriguian will remain for now the (medical) reviewer," he would "likely" be replaced. Fleming said last week he did not recall making a "commitment" to Taylor that he would remove Gueriguian from the review of Rezulin if she became displeased.

After Warner-Lambert complained in October 1996 that Gueriguian used a vulgarity to describe Rezulin, the FDA stripped him of any further role with the drug. By that time, the veteran medical officer was recommending rejection of the pill, warning in a written review of its potential to harm the liver and the heart. He also questioned its worthiness as a blood-sugar-lowering agent.

'Out of the picture'

The FDA's banishment of Gueriguian clearly pleased Warner-Lambert's executive vice president for regulatory affairs, Irwin Martin, who e-mailed colleagues on Oct. 16, 1996, saying, "We're over the JG hurdle." Martin wrote that Fleming assured him, "John (Gueriguian) is `out of the picture.' His review is complete. ... It will not go to the advisory committee." Gueriguian was formally removed from the review of Rezulin on Nov. 4, 1996.

On Dec. 2, 1996 - nine days before the FDA advisory committee would meet to consider Rezulin's approval - Fleming e-mailed Martin an encrypted copy of Gueriguian's medical review. That same day, Fleming wrote in a separate e-mail to colleagues that Lumpkin had told him Gueriguian's review "is not FOIable." By this, Fleming suggested the document would be withheld from public view because consumers, the news media or others could not obtain it under the Freedom of Information Act. The FDA staff withheld the existence of Gueriguian's review from members of the advisory committee. Lumpkin, at the time the No. 2 official of the agency's drug-review center, did not return calls last week.

On Dec. 9, 1996, two days before the advisory committee meeting, Fleming e-mailed Martin: "The drug looks like it ought to be on the market. Loosen up and put on a good presentation. Call if you need help."

Senior agency officials remained helpful as the company pushed to keep Rezulin on the U.S. market in the face of the ever-mounting liver failures and deaths and the withdrawal of the product from Britain. On June 6, 1998, just days after the NIH banished Rezulin from its study, Martin wrote in a company memo that he had discussed "the current Rezulin issues" with Lumpkin while the two attended a drug-industry trade group gathering. According to Martin's memo, a subordinate of Lumpkin, Dr. James Bilstad, at that time was considering a change in Rezulin's labeling that could have dealt a crippling blow to the drug: a recommendation for twice-a-month liver testing for all patients.

Publicly, the company and the FDA were still assuring doctors that the risk of liver failure was very rare and could be managed with once-a-month monitoring for the first half-year of use. Martin wrote that he and Lumpkin "discussed alternatives" to the imposition of twice-monthly monitoring.

Discussion of Rezulin shelved

"He (Lumpkin) also agreed that we need to evaluate these (liver-failure) cases, and not simply act because NIH did." The FDA abandoned the idea of recommending twice-monthly monitoring and continued to assure doctors that Rezulin could be used safely. In the same memo, Martin said that he expressed "concern" to Lumpkin about the FDA's Misbin. The previous month Misbin was instructed by his bosses to cancel his commitment to discuss Rezulin and its liver toxicity at a public conference in the Washington area.

"I thanked Mac for his help on the last issue with Misbin wanting to speak publicly about Rezulin hepatotox," Martin wrote, adding in a subsequent e-mail that Misbin's appearance was "canceled by Mac."

Lumpkin also encouraged Warner-Lambert to forcefully highlight anecdotes of happy Rezulin patients, Martin wrote in his June 6, 1998, e-mail. "Mac suggested those stories need to come out."

Pfizer, in a financial statement last fall to the Securities and Exchange Commission, said that as of mid-October it was defending against 383 Rezulin-related lawsuits filed in state and federal courts. In addition to the civil suits, prosecutors with the U.S. Attorney's Office in Greenbelt, Md., began questioning FDA officials last year about circumstances surrounding the approval of Rezulin.

Copyright © 2001 The Seattle Times Company


January 18, 2000

MORE THAN HALF OF AMERICANS AT RISK OF DRUG INTERACTIONS


The Alternative Medicine Newsletter tells us about a disturbing survey reported by the American Society of Health-System Pharmacists (ASHP) which found that more than half of all Americans are at risk of possible drug interactions.

The survey found that of 1000 American questioned,
*46% take at least one prescription medicine every day.
*25% take multiple prescription medicines daily.
*56% had taken 2 over-the-counter medications or supplements in the week before they were surveyed.
*39% surveyed tell their doctor or nurse about their drug use
*8% failed to tell them at all

Mick Hunt, president of the ASHP says that "as you take more medications [the] opportunity for drug interactions grows."E."healthcare providers need to do a little bit better job at pulling that information out," but ultimately the pharmacist is better qualified at helping patients be better informed on the dangers of the drugs they are taking and how they interact.

Commentary: Seems to us the safest approach may be to rely less on dangerous drugs and more on a properly functioning body, maintained through Chiropractic Wellness CareE.Dr. Acosta


February 14, 2001

FLUORIDE INDUCED AILMENTS WIDESPREAD


Alternative Medicine Newsletter:
Millions of people throughout India, China and parts of Africa currently suffer from various forms of fluoride toxicity and that millions of Americans may be suffering from it as well. Fluoride has been added to the nation's water supply for years as a tooth decay preventative and has been touted by some as being safe. Not so, says Paul Connett, PhD of the Fluoride Action Network (FAN). Millions of people around the world are suffering from a form of fluoride poisoning known as skeletal fluorosis. The symptoms of skeletal fluorosis very closely mimic the symptoms of arthritis and include chronic joint pain, muscle wasting, calcification of spinal structures and bone deformities. According to the Journal of the American Chemical Society, "the first two clinical phases [of skeletal fluorosis] could be easily misdiagnosed" as arthritis. The journal also goes on to report that "virtually no research" has been done to determine how much misdiagnosis occursEEr. Connett goes on to say that Americans are exposed to high levels of fluoride through fluoridated water, dental products and pesticide residues. He warns that continued exposure to fluoride may well be a contributing factor to the greatly increased levels of arthritis in the U.S., particularly in the elderly.

More information on this story can be found at www.fluoridealert.org